Application of locked nucleic acids to improve aptamer in vivo stability and targeting function

Aptamers are powerful candidates for molecular imaging applications due to a number of attractive features, including rapid blood clearance and tumor penetration. We carried out structure–activity relationship (SAR) studies with the Tenascin-C binding aptamer TTA1, which is a promising candidate for...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Schmidt, Kathrin S., Borkowski, Sandra, Kurreck, Jens, Stephens, Andrew W., Bald, Rolf, Hecht, Maren, Friebe, Matthias, Dinkelborg, Ludger, Erdmann, Volker A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2004
Onderwerpen:
Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC528785/
https://ncbi.nlm.nih.gov/pubmed/15509871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh862
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items