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Using reference-free compressed data structures to analyze sequencing reads from thousands of human genomes
We are rapidly approaching the point where we have sequenced millions of human genomes. There is a pressing need for new data structures to store raw sequencing data and efficient algorithms for population scale analysis. Current reference-based data formats do not fully exploit the redundancy in po...
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| I publikationen: | Genome Res |
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| Huvudupphovsmän: | , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cold Spring Harbor Laboratory Press
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5287235/ https://ncbi.nlm.nih.gov/pubmed/27986821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.211748.116 |
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