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Crumble: reference free lossy compression of sequence quality values
MOTIVATION: The bulk of space taken up by NGS sequencing CRAM files consists of per-base quality values. Most of these are unnecessary for variant calling, offering an opportunity for space saving. RESULTS: On the Syndip test set, a 17 fold reduction in the quality storage portion of a CRAM file can...
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| Izdano u: | Bioinformatics |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6330002/ https://ncbi.nlm.nih.gov/pubmed/29992288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty608 |
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