Comparative analyses of super-enhancers reveal conserved elements in vertebrate genomes

Super-enhancers (SEs) are key transcriptional drivers of cellular, developmental, and disease states in mammals, yet the conservational and regulatory features of these enhancer elements in nonmammalian vertebrates are unknown. To define SEs in zebrafish and enable sequence and functional comparison...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Res
Prif Awduron: Pérez-Rico, Yuvia A., Boeva, Valentina, Mallory, Allison C., Bitetti, Angelo, Majello, Sara, Barillot, Emmanuel, Shkumatava, Alena
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2017
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287231/
https://ncbi.nlm.nih.gov/pubmed/27965291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.203679.115
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