Strategies for genetic inactivation of long noncoding RNAs in zebrafish

The number of annotated long noncoding RNAs (lncRNAs) continues to grow; however, their functional characterization in model organisms has been hampered by the lack of reliable genetic inactivation strategies. While partial or full deletions of lncRNA loci disrupt lncRNA expression, they do not perm...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:RNA
Prif Awduron: Lavalou, Perrine, Eckert, Helene, Damy, Louise, Constanty, Florian, Majello, Sara, Bitetti, Angelo, Graindorge, Antoine, Shkumatava, Alena
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2019
Pynciau:
Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633201/
https://ncbi.nlm.nih.gov/pubmed/31043511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.069484.118
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