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Strategies for genetic inactivation of long noncoding RNAs in zebrafish

The number of annotated long noncoding RNAs (lncRNAs) continues to grow; however, their functional characterization in model organisms has been hampered by the lack of reliable genetic inactivation strategies. While partial or full deletions of lncRNA loci disrupt lncRNA expression, they do not perm...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Lavalou, Perrine, Eckert, Helene, Damy, Louise, Constanty, Florian, Majello, Sara, Bitetti, Angelo, Graindorge, Antoine, Shkumatava, Alena
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633201/
https://ncbi.nlm.nih.gov/pubmed/31043511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.069484.118
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