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Comparative analyses of super-enhancers reveal conserved elements in vertebrate genomes

Super-enhancers (SEs) are key transcriptional drivers of cellular, developmental, and disease states in mammals, yet the conservational and regulatory features of these enhancer elements in nonmammalian vertebrates are unknown. To define SEs in zebrafish and enable sequence and functional comparison...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Pérez-Rico, Yuvia A., Boeva, Valentina, Mallory, Allison C., Bitetti, Angelo, Majello, Sara, Barillot, Emmanuel, Shkumatava, Alena
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287231/
https://ncbi.nlm.nih.gov/pubmed/27965291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.203679.115
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