Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes

Transcriptional enhancers are critical for maintaining cell-type–specific gene expression and driving cell fate changes during development. Highly transcribed genes are often associated with a cluster of individual enhancers such as those found in locus control regions. Recently, these have been ter...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Genome Res
Autori principali: Moorthy, Sakthi D., Davidson, Scott, Shchuka, Virlana M., Singh, Gurdeep, Malek-Gilani, Nakisa, Langroudi, Lida, Martchenko, Alexandre, So, Vincent, Macpherson, Neil N., Mitchell, Jennifer A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287230/
https://ncbi.nlm.nih.gov/pubmed/27895109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.210930.116
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