A Sox2 distal enhancer cluster regulates embryonic stem cell differentiation potential

The Sox2 transcription factor must be robustly transcribed in embryonic stem (ES) cells to maintain pluripotency. Two gene-proximal enhancers, Sox2 regulatory region 1 (SRR1) and SRR2, display activity in reporter assays, but deleting SRR1 has no effect on pluripotency. We identified and functionall...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteurs: Zhou, Harry Y., Katsman, Yulia, Dhaliwal, Navroop K., Davidson, Scott, Macpherson, Neil N., Sakthidevi, Moorthy, Collura, Felicia, Mitchell, Jennifer A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2014
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265674/
https://ncbi.nlm.nih.gov/pubmed/25512558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.248526.114
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items