Necroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in mice

Acquired aplastic anemia is an autoimmune-mediated bone marrow failure syndrome. The mechanism by which such an autoimmune reaction is initiated is unknown. Whether and how the genetic lesions detected in patients cause autoimmune bone marrow failure have not yet been determined. We found that mice...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Xin, Junping, Breslin, Peter, Wei, Wei, Li, Jing, Gutierrez, Rafael, Cannova, Joseph, Ni, Allen, Ng, Grace, Schmidt, Rachel, Chen, Haiyan, Parini, Vamsi, Kuo, Paul C., Kini, Ameet R., Stiff, Patrick, Zhu, Jiang, Zhang, Jiwang
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286937/
https://ncbi.nlm.nih.gov/pubmed/27634200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.151514
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