VEGF blockade enhances the antitumor effect of BRAF(V) (600E) inhibition

The development of resistance remains a major obstacle to long‐term disease control in cancer patients treated with targeted therapies. In BRAF‐mutant mouse models, we demonstrate that although targeted inhibition of either BRAF or VEGF initially suppresses the growth of BRAF‐mutant tumors, combined...

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Foilsithe in:EMBO Mol Med
Main Authors: Comunanza, Valentina, Corà, Davide, Orso, Francesca, Consonni, Francesca Maria, Middonti, Emanuele, Di Nicolantonio, Federica, Buzdin, Anton, Sica, Antonio, Medico, Enzo, Sangiolo, Dario, Taverna, Daniela, Bussolino, Federico
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
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Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286370/
https://ncbi.nlm.nih.gov/pubmed/27974353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505774
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