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Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma

Combining immunotherapy and BRAF targeted therapy may result in improved antitumor activity with the high response rates of targeted therapy and the durability of responses with immunotherapy. However, the first clinical trial testing the combination of the BRAF inhibitor vemurafenib and the CTLA-4...

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Publicat a:Sci Transl Med
Autors principals: Hu-Lieskovan, Siwen, Mok, Stephen, Moreno, Blanca Homet, Tsoi, Jennifer, Faja, Lidia Robert, Goedert, Lucas, Pinheiro, Elaine M., Koya, Richard C., Graeber, Thomas, Comin-Anduix, Begoña, Ribas, Antoni
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765379/
https://ncbi.nlm.nih.gov/pubmed/25787767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa4691
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