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Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma

Combining immunotherapy and BRAF targeted therapy may result in improved antitumor activity with the high response rates of targeted therapy and the durability of responses with immunotherapy. However, the first clinical trial testing the combination of the BRAF inhibitor vemurafenib and the CTLA-4...

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Podrobná bibliografie
Vydáno v:Sci Transl Med
Hlavní autoři: Hu-Lieskovan, Siwen, Mok, Stephen, Moreno, Blanca Homet, Tsoi, Jennifer, Faja, Lidia Robert, Goedert, Lucas, Pinheiro, Elaine M., Koya, Richard C., Graeber, Thomas, Comin-Anduix, Begoña, Ribas, Antoni
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765379/
https://ncbi.nlm.nih.gov/pubmed/25787767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa4691
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