Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition

BACKGROUND: Malignant melanoma is an aggressive tumor type that often develops drug resistance to targeted therapeutics. The production of colony stimulating factor 1 (CSF-1) in tumors recruits myeloid cells such as M2-polarized macrophages and myeloid derived suppressor cells (MDSC), leading to an...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :BMC Cancer
Главные авторы: Mok, Stephen, Tsoi, Jennifer, Koya, Richard C, Hu-Lieskovan, Siwen, West, Brian L, Bollag, Gideon, Graeber, Thomas G, Ribas, Antoni
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432503/
https://ncbi.nlm.nih.gov/pubmed/25939769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1377-8
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы