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Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition
BACKGROUND: Malignant melanoma is an aggressive tumor type that often develops drug resistance to targeted therapeutics. The production of colony stimulating factor 1 (CSF-1) in tumors recruits myeloid cells such as M2-polarized macrophages and myeloid derived suppressor cells (MDSC), leading to an...
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| Publicado no: | BMC Cancer |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4432503/ https://ncbi.nlm.nih.gov/pubmed/25939769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1377-8 |
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