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Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma

Combining immunotherapy and BRAF targeted therapy may result in improved antitumor activity with the high response rates of targeted therapy and the durability of responses with immunotherapy. However, the first clinical trial testing the combination of the BRAF inhibitor vemurafenib and the CTLA-4...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Transl Med
Päätekijät: Hu-Lieskovan, Siwen, Mok, Stephen, Moreno, Blanca Homet, Tsoi, Jennifer, Faja, Lidia Robert, Goedert, Lucas, Pinheiro, Elaine M., Koya, Richard C., Graeber, Thomas, Comin-Anduix, Begoña, Ribas, Antoni
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765379/
https://ncbi.nlm.nih.gov/pubmed/25787767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa4691
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