Ligand-stimulated signaling events in immature CD4+CD8+ thymocytes expressing competent T-cell receptor complexes.

During thymic selection of the developing T-cell repertoire, the fate of individual CD4+CD8+ thymocytes is determined by the specificity of the T-cell antigen receptors (TCRs) they express. Paradoxically, most CD4+CD8+ thymocytes express few TCR molecules, and those they express are essentially inca...

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Détails bibliographiques
Auteurs principaux: Nakayama, T, Samelson, L E, Nakayama, Y, Munitz, T I, Sheard, M, June, C H, Singer, A
Format: Artigo
Langue:Inglês
Publié: 1991
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC52844/
https://ncbi.nlm.nih.gov/pubmed/1719558
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