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Enhancing the clinical coverage and anticancer efficacy of immune checkpoint blockade through manipulation of the gut microbiota

Although anticancer therapy with immune checkpoint blockers has seen unprecedented success, it fails to control neoplasia in most patients and often causes immune-related adverse events (irAEs). Our recent research shows the immunostimulatory and antitumor effects of CTLA-4 blockade depend on distin...

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Détails bibliographiques
Publié dans:Oncoimmunology
Auteurs principaux: Pitt, Jonathan M., Vétizou, Marie, Gomperts Boneca, Ivo, Lepage, Patricia, Chamaillard, Mathias, Zitvogel, Laurence
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283646/
https://ncbi.nlm.nih.gov/pubmed/28197360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1132137
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