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Why should we need the gut microbiota to respond to cancer therapies?

Cyclophosphamide, one of the most efficient tumoricidal, antiangiogenic, and immunostimulatory drugs employed to date mediates part of its effects through intestinal bacteria, against which the host becomes immunized during treatment. Our recent work suggests that anti-commensal effector pT(H)17 and...

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Hlavní autoři: Viaud, Sophie, Daillère, Romain, Yamazaki, Takahiro, Lepage, Patricia, Boneca, Ivo, Goldszmid, Romina, Trinchieri, Giorgio, Zitvogel, Laurence
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006853/
https://ncbi.nlm.nih.gov/pubmed/24800167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27574
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