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Enhancing the clinical coverage and anticancer efficacy of immune checkpoint blockade through manipulation of the gut microbiota

Although anticancer therapy with immune checkpoint blockers has seen unprecedented success, it fails to control neoplasia in most patients and often causes immune-related adverse events (irAEs). Our recent research shows the immunostimulatory and antitumor effects of CTLA-4 blockade depend on distin...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Pitt, Jonathan M., Vétizou, Marie, Gomperts Boneca, Ivo, Lepage, Patricia, Chamaillard, Mathias, Zitvogel, Laurence
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283646/
https://ncbi.nlm.nih.gov/pubmed/28197360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1132137
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