Rab22a controls MHC‐I intracellular trafficking and antigen cross‐presentation by dendritic cells

Cross‐presentation by MHC class I molecules allows the detection of exogenous antigens by CD8(+) T lymphocytes. This process is crucial to initiate cytotoxic immune responses against many pathogens (i.e., Toxoplasma gondii) and tumors. To achieve efficient cross‐presentation, dendritic cells (DCs) h...

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Vydáno v:EMBO Rep
Hlavní autoři: Cebrian, Ignacio, Croce, Cristina, Guerrero, Néstor A, Blanchard, Nicolas, Mayorga, Luis S
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Scientific Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283579/
https://ncbi.nlm.nih.gov/pubmed/27861124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642358
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