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Rab22a controls MHC‐I intracellular trafficking and antigen cross‐presentation by dendritic cells
Cross‐presentation by MHC class I molecules allows the detection of exogenous antigens by CD8(+) T lymphocytes. This process is crucial to initiate cytotoxic immune responses against many pathogens (i.e., Toxoplasma gondii) and tumors. To achieve efficient cross‐presentation, dendritic cells (DCs) h...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283579/ https://ncbi.nlm.nih.gov/pubmed/27861124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642358 |
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