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Intracellular Transport Routes for MHC I and Their Relevance for Antigen Cross-Presentation

Cross-presentation, in which exogenous antigens are presented via MHC I complexes, is involved both in the generation of anti-infectious and anti-tumoral cytotoxic CD8(+) T cells and in the maintenance of immune tolerance. While cross-presentation was described almost four decades ago and while it i...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Adiko, Aimé Cézaire, Babdor, Joel, Gutiérrez-Martínez, Enric, Guermonprez, Pierre, Saveanu, Loredana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489332/
https://ncbi.nlm.nih.gov/pubmed/26191062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00335
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