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Progranulin causes adipose insulin resistance via increased autophagy resulting from activated oxidative stress and endoplasmic reticulum stress
BACKGROUND: Progranulin (PGRN) has recently emerged as an important regulator for insulin resistance. However, the direct effect of progranulin in adipose insulin resistance associated with the autophagy mechanism is not fully understood. METHODS: In the present study, progranulin was administered t...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Lipids Health Dis |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5282713/ https://ncbi.nlm.nih.gov/pubmed/28143512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-017-0425-6 |
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