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Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs
Therapeutic nucleic acids hold great promise for the treatment of disease but require vectors for safe and effective delivery. Synthetic nanoparticle vectors composed of poly(β-amino esters) (PBAEs) and nucleic acids have previously demonstrated potential utility for local delivery applications. To...
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| Publicado en: | Angew Chem Int Ed Engl |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5279893/ https://ncbi.nlm.nih.gov/pubmed/27690187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201608450 |
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