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Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice

The vitamin B(12) analog hydroxy-cobalamin[c-lactam] (HCCL) impairs hepatic mitochondrial protein synthesis and function of the electron transport chain in rats. We aimed to establish an in vivo model for mitochondrial dysfunction in mice, which could be used to investigate hepatotoxicity of mitocho...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Haegler, Patrizia, Grünig, David, Berger, Benjamin, Terracciano, Luigi, Krähenbühl, Stephan, Bouitbir, Jamal
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279765/
https://ncbi.nlm.nih.gov/pubmed/28135329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171026
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