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Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice
The vitamin B(12) analog hydroxy-cobalamin[c-lactam] (HCCL) impairs hepatic mitochondrial protein synthesis and function of the electron transport chain in rats. We aimed to establish an in vivo model for mitochondrial dysfunction in mice, which could be used to investigate hepatotoxicity of mitocho...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5279765/ https://ncbi.nlm.nih.gov/pubmed/28135329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171026 |
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