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Extra-nuclear effects of estrogen on cortical bone in males require ERαAF-1

Estradiol (E2) signaling via estrogen receptor alpha (ERα) is important for the male skeleton as demonstrated by ERα inactivation in both mice and man. ERα mediates estrogenic effects not only by translocating to the nucleus and affecting gene transcription but also by extra-nuclear actions e.g., tr...

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Publicado en:J Mol Endocrinol
Autores principales: Farman, H H, Wu, J, Gustafsson, K L, Windahl, S H, Kim, S H, Katzenellenbogen, J A, Ohlsson, C, Lagerquist, M K
Formato: Artigo
Lenguaje:Inglês
Publicado: Bioscientifica Ltd 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278601/
https://ncbi.nlm.nih.gov/pubmed/28057769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-16-0209
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