The effect of estrogen on bone requires ERα in nonhematopoietic cells but is enhanced by ERα in hematopoietic cells

The effects of estrogen on bone are mediated mainly via estrogen receptor (ER)α. ERα in osteoclasts (hematopoietic origin) is involved in the trabecular bone-sparing effects of estrogen, but conflicting data are reported on the role of ERα in osteoblast lineage cells (nonhematopoietic origin) for bo...

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Main Authors: Henning, Petra, Ohlsson, Claes, Engdahl, Cecilia, Farman, Helen, Windahl, Sara H., Carlsten, Hans, Lagerquist, Marie K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2014
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187026/
https://ncbi.nlm.nih.gov/pubmed/25117411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00255.2014
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