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Extra-nuclear effects of estrogen on cortical bone in males require ERαAF-1

Estradiol (E2) signaling via estrogen receptor alpha (ERα) is important for the male skeleton as demonstrated by ERα inactivation in both mice and man. ERα mediates estrogenic effects not only by translocating to the nucleus and affecting gene transcription but also by extra-nuclear actions e.g., tr...

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Bibliographic Details
Published in:J Mol Endocrinol
Main Authors: Farman, H H, Wu, J, Gustafsson, K L, Windahl, S H, Kim, S H, Katzenellenbogen, J A, Ohlsson, C, Lagerquist, M K
Format: Artigo
Language:Inglês
Published: Bioscientifica Ltd 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278601/
https://ncbi.nlm.nih.gov/pubmed/28057769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-16-0209
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