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Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP
ABC transporters form one of the largest protein superfamilies in all domains of life, catalyzing the movement of diverse substrates across membranes. In this key position, ABC transporters can mediate multidrug resistance in cancer therapy and their dysfunction is linked to various diseases. Here,...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5278451/ https://ncbi.nlm.nih.gov/pubmed/28069938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620009114 |
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