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Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP

ABC transporters form one of the largest protein superfamilies in all domains of life, catalyzing the movement of diverse substrates across membranes. In this key position, ABC transporters can mediate multidrug resistance in cancer therapy and their dysfunction is linked to various diseases. Here,...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nöll, Anne, Thomas, Christoph, Herbring, Valentina, Zollmann, Tina, Barth, Katja, Mehdipour, Ahmad Reza, Tomasiak, Thomas M., Brüchert, Stefan, Joseph, Benesh, Abele, Rupert, Oliéric, Vincent, Wang, Meitian, Diederichs, Kay, Hummer, Gerhard, Stroud, Robert M., Pos, Klaas M., Tampé, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278451/
https://ncbi.nlm.nih.gov/pubmed/28069938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620009114
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