Signal mingle: Micropatterns of BMP-2 and fibronectin on soft biopolymeric films regulate myoblast shape and SMAD signaling

In vivo, bone morphogenetic protein 2 (BMP-2) exists both in solution and bound to the extracellular matrix (ECM). While these two modes of presentation are known to influence cell behavior distinctly, their role in the niche microenvironment and their functional relevance in the genesis of a biolog...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Fitzpatrick, Vincent, Fourel, Laure, Destaing, Olivier, Gilde, Flora, Albigès-Rizo, Corinne, Picart, Catherine, Boudou, Thomas
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278375/
https://ncbi.nlm.nih.gov/pubmed/28134270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41479
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