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Signal mingle: Micropatterns of BMP-2 and fibronectin on soft biopolymeric films regulate myoblast shape and SMAD signaling

In vivo, bone morphogenetic protein 2 (BMP-2) exists both in solution and bound to the extracellular matrix (ECM). While these two modes of presentation are known to influence cell behavior distinctly, their role in the niche microenvironment and their functional relevance in the genesis of a biolog...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Fitzpatrick, Vincent, Fourel, Laure, Destaing, Olivier, Gilde, Flora, Albigès-Rizo, Corinne, Picart, Catherine, Boudou, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278375/
https://ncbi.nlm.nih.gov/pubmed/28134270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41479
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