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Spatial patterning of BMP-2 and BMP-7 on biopolymeric films and the guidance of muscle cell fate

In the cellular microenvironment, growth factor gradients are crucial in dictating cell fate. Towards developing materials that capture the native microenvironment we engineered biomimetic films that present gradients of matrix-bound bone morphogenetic proteins (BMP-2 and BMP-7). To this end layer-b...

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Detalhes bibliográficos
Main Authors: Almodóvar, Jorge, Guillot, Raphaël, Monge, Claire, Vollaire, Julien, Selimović, Šeila, Luc-Coll, Jean, Khademhosseini, Ali, Picart, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155073/
https://ncbi.nlm.nih.gov/pubmed/24485790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.01.012
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