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Spatial patterning of BMP-2 and BMP-7 on biopolymeric films and the guidance of muscle cell fate

In the cellular microenvironment, growth factor gradients are crucial in dictating cell fate. Towards developing materials that capture the native microenvironment we engineered biomimetic films that present gradients of matrix-bound bone morphogenetic proteins (BMP-2 and BMP-7). To this end layer-b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Almodóvar, Jorge, Guillot, Raphaël, Monge, Claire, Vollaire, Julien, Selimović, Šeila, Luc-Coll, Jean, Khademhosseini, Ali, Picart, Catherine
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155073/
https://ncbi.nlm.nih.gov/pubmed/24485790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.01.012
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