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Spatial patterning of BMP-2 and BMP-7 on biopolymeric films and the guidance of muscle cell fate

In the cellular microenvironment, growth factor gradients are crucial in dictating cell fate. Towards developing materials that capture the native microenvironment we engineered biomimetic films that present gradients of matrix-bound bone morphogenetic proteins (BMP-2 and BMP-7). To this end layer-b...

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Bibliografiske detaljer
Main Authors: Almodóvar, Jorge, Guillot, Raphaël, Monge, Claire, Vollaire, Julien, Selimović, Šeila, Luc-Coll, Jean, Khademhosseini, Ali, Picart, Catherine
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155073/
https://ncbi.nlm.nih.gov/pubmed/24485790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.01.012
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