Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation

Acetyl-CoA is a key metabolic intermediate with an important role in transcriptional regulation. The nuclear-cytosolic acetyl-CoA synthetase 2 (ACSS2) was found to sustain the growth of hypoxic tumor cells. It generates acetyl-CoA from acetate, but exactly which pathways it supports is not fully und...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Bulusu, Vinay, Tumanov, Sergey, Michalopoulou, Evdokia, van den Broek, Niels J., MacKay, Gillian, Nixon, Colin, Dhayade, Sandeep, Schug, Zachary T., Vande Voorde, Johan, Blyth, Karen, Gottlieb, Eyal, Vazquez, Alexei, Kamphorst, Jurre J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5276806/
https://ncbi.nlm.nih.gov/pubmed/28099844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.055
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados