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How does leptin restore euglycemia in insulin-deficient diabetes?

Insulin replacement is the cornerstone of type 1 diabetes (T1D) treatment; however, glycemic control remains a challenge. Leptin has been shown to effectively restore euglycemia in rodent models of T1D; however, the mechanism or mechanisms by which leptin exerts glycemic control are unclear. In this...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Oberlin, Douglas, Buettner, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5272168/
https://ncbi.nlm.nih.gov/pubmed/28112680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91880
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