Leptin Deficiency Causes Insulin Resistance Induced by Uncontrolled Diabetes

OBJECTIVE: Depletion of body fat stores during uncontrolled, insulin-deficient diabetes (uDM) results in markedly reduced plasma leptin levels. This study investigated the role of leptin deficiency in the genesis of severe insulin resistance and related metabolic and neuroendocrine derangements indu...

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Detaylı Bibliyografya
Asıl Yazarlar: German, Jonathan P., Wisse, Brent E., Thaler, Joshua P., Oh-I, Shinsuke, Sarruf, David A., Ogimoto, Kayoko, Kaiyala, Karl J., Fischer, Jonathan D., Matsen, Miles E., Taborsky, Gerald J., Schwartz, Michael W., Morton, Gregory J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2010
Konular:
Metabolism
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889761/
https://ncbi.nlm.nih.gov/pubmed/20424233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1918
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