Leptin Activates a Novel CNS Mechanism for Insulin-Independent Normalization of Severe Diabetic Hyperglycemia

The brain has emerged as a target for the insulin-sensitizing effects of several hormonal and nutrient-related signals. The current studies were undertaken to investigate mechanisms whereby leptin lowers circulating blood glucose levels independently of insulin. After extending previous evidence tha...

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Autori principali: German, Jonathan P., Thaler, Joshua P., Wisse, Brent E., Oh-I, Shinsuke, Sarruf, David A., Matsen, Miles E., Fischer, Jonathan D., Taborsky, Gerald J., Schwartz, Michael W., Morton, Gregory J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2011
Soggetti:
Diabetes-Insulin-Glucagon-Gastrointestinal
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037161/
https://ncbi.nlm.nih.gov/pubmed/21159853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0890
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