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Euglycemia Restoration by Central Leptin in Type 1 Diabetes Requires STAT3 Signaling but Not Fast-Acting Neurotransmitter Release

Central leptin action is sufficient to restore euglycemia in insulinopenic type 1 diabetes (T1D); however, the underlying mechanism remains poorly understood. To examine the role of intracellular signal transducer and activator of transcription 3 (STAT3) pathways, we used LepRs/s mice with disrupted...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Xu, Yuanzhong, Chang, Jeffrey T., Myers, Martin G., Xu, Yong, Tong, Qingchun
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806656/
https://ncbi.nlm.nih.gov/pubmed/26822087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1160
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