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eIF4B stimulates eIF4A ATPase and unwinding activities by direct interaction through its 7-repeats region

Eukaryotic translation initiation starts with binding of the eIF4F complex to the 5′-m(7)G cap of the mRNA. Recruitment of the 43S pre-initiation complex (PIC), formed by the 40S ribosomal subunit and other translation initiation factors, leads to formation of the 48S PIC that then scans the 5′-untr...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Andreou, Alexandra Zoi, Harms, Ulf, Klostermeier, Dagmar
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270515/
https://ncbi.nlm.nih.gov/pubmed/27858515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1259782
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