FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders

OBJECTIVE: To validate new mitochondrial myopathy serum biomarkers for diagnostic use. METHODS: We analyzed serum FGF21 (S-FGF21) and GDF15 from patients with (1) mitochondrial diseases and (2) nonmitochondrial disorders partially overlapping with mitochondrial disorder phenotypes. We (3) did a meta...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Neurology
Autores principales: Lehtonen, Jenni M., Forsström, Saara, Bottani, Emanuela, Viscomi, Carlo, Baris, Olivier R., Isoniemi, Helena, Höckerstedt, Krister, Österlund, Pia, Hurme, Mikko, Jylhävä, Juulia, Leppä, Sirpa, Markkula, Ritva, Heliö, Tiina, Mombelli, Giuliana, Uusimaa, Johanna, Laaksonen, Reijo, Laaksovirta, Hannu, Auranen, Mari, Zeviani, Massimo, Smeitink, Jan, Wiesner, Rudolf J., Nakada, Kazuto, Isohanni, Pirjo, Suomalainen, Anu
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270510/
https://ncbi.nlm.nih.gov/pubmed/27794108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000003374
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares