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Increased Paternal Age at Conception Is Associated with Transcriptomic Changes Involved in Mitochondrial Function in Elderly Individuals

The increased paternal age at conception (PAC) has been associated with autism spectrum disorder (ASD), schizophrenia and other neurodevelopmental disorders, thus raising questions that imply, potential health concerns in the offspring. As opposed to female oogonia, the male germ cells undergo hundr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nevalainen, Tapio, Kananen, Laura, Marttila, Saara, Jylhävä, Juulia, Jylhä, Marja, Hervonen, Antti, Hurme, Mikko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120832/
https://ncbi.nlm.nih.gov/pubmed/27880854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167028
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