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Length of paternal lifespan is manifested in the DNA methylome of their nonagenarian progeny

The heritability of lifespan is 20-30%, but only a few genes associated with longevity have been identified. To explain this discrepancy, the inheritance of epigenetic features, such as DNA methylation, have been proposed to contribute to the heritability of lifespan. We investigated whether parenta...

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書目詳細資料
發表在:Oncotarget
Main Authors: Marttila, Saara, Kananen, Laura, Jylhävä, Juulia, Nevalainen, Tapio, Hervonen, Antti, Jylhä, Marja, Hurme, Mikko
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741551/
https://ncbi.nlm.nih.gov/pubmed/26436701
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