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Length of paternal lifespan is manifested in the DNA methylome of their nonagenarian progeny

The heritability of lifespan is 20-30%, but only a few genes associated with longevity have been identified. To explain this discrepancy, the inheritance of epigenetic features, such as DNA methylation, have been proposed to contribute to the heritability of lifespan. We investigated whether parenta...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Marttila, Saara, Kananen, Laura, Jylhävä, Juulia, Nevalainen, Tapio, Hervonen, Antti, Jylhä, Marja, Hurme, Mikko
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741551/
https://ncbi.nlm.nih.gov/pubmed/26436701
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