Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression

BACKGROUND: Changes in DNA methylation are among the mechanisms contributing to the ageing process. We sought to identify ageing-associated DNA methylation changes at single-CpG-site resolution in blood leukocytes and to ensure that the observed changes were not due to differences in the proportions...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Marttila, Saara, Kananen, Laura, Häyrynen, Sergei, Jylhävä, Juulia, Nevalainen, Tapio, Hervonen, Antti, Jylhä, Marja, Nykter, Matti, Hurme, Mikko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404609/
https://ncbi.nlm.nih.gov/pubmed/25888029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1381-z
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