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Increased Paternal Age at Conception Is Associated with Transcriptomic Changes Involved in Mitochondrial Function in Elderly Individuals

The increased paternal age at conception (PAC) has been associated with autism spectrum disorder (ASD), schizophrenia and other neurodevelopmental disorders, thus raising questions that imply, potential health concerns in the offspring. As opposed to female oogonia, the male germ cells undergo hundr...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Nevalainen, Tapio, Kananen, Laura, Marttila, Saara, Jylhävä, Juulia, Jylhä, Marja, Hervonen, Antti, Hurme, Mikko
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120832/
https://ncbi.nlm.nih.gov/pubmed/27880854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167028
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