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Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice
Bone morphogenetic protein 6 (BMP6) signaling in hepatocytes is a central transcriptional regulator of the iron hormone hepcidin that controls systemic iron balance. How iron levels are sensed to regulate hepcidin production is not known, but local induction of liver BMP6 expression by iron is propo...
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| Yayımlandı: | Blood |
|---|---|
| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society of Hematology
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5270389/ https://ncbi.nlm.nih.gov/pubmed/27864295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-06-721571 |
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