Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types

BACKGROUND: A healthy immune system requires immune cells that adapt rapidly to environmental challenges. This phenotypic plasticity can be mediated by transcriptional and epigenetic variability. RESULTS: We apply a novel analytical approach to measure and compare transcriptional and epigenetic vari...

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Bibliografiska uppgifter
I publikationen:Genome Biol
Huvudupphovsmän: Ecker, Simone, Chen, Lu, Pancaldi, Vera, Bagger, Frederik O., Fernández, José María, Carrillo de Santa Pau, Enrique, Juan, David, Mann, Alice L., Watt, Stephen, Casale, Francesco Paolo, Sidiropoulos, Nikos, Rapin, Nicolas, Merkel, Angelika, Stunnenberg, Hendrik G., Stegle, Oliver, Frontini, Mattia, Downes, Kate, Pastinen, Tomi, Kuijpers, Taco W., Rico, Daniel, Valencia, Alfonso, Beck, Stephan, Soranzo, Nicole, Paul, Dirk S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2017
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270224/
https://ncbi.nlm.nih.gov/pubmed/28126036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1156-8
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