Identification of MiR-21-5p as a Functional Regulator of Mesothelin Expression Using MicroRNA Capture Affinity Coupled with Next Generation Sequencing

MicroRNAs (miRNAs) are small non-coding RNAs that regulate mRNA expression mainly by silencing target transcripts via binding to miRNA recognition elements (MREs) in the 3’untranslated region (3’UTR). The identification of bona fide targets is challenging for researchers working on the functional as...

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Udgivet i:PLoS One
Main Authors: De Santi, Chiara, Vencken, Sebastian, Blake, Jonathon, Haase, Bettina, Benes, Vladimir, Gemignani, Federica, Landi, Stefano, Greene, Catherine M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268774/
https://ncbi.nlm.nih.gov/pubmed/28125734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170999
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