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A novel high affinity human monoclonal antibody to mesothelin

Mesothelin is a glycosylphosphatidylinisotol-anchored glycoprotein that is highly expressed on the cell surface of mesothelioma, ovarian cancer and other malignant tumors. The interaction between mesothelin and CA125 (also called MUC16) may facilitate the implantation and metastasis of tumors in the...

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Autors principals: Ho, Mitchell, Feng, Mingqian, Fisher, Robert J., Rader, Christoph, Pastan, Ira
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978266/
https://ncbi.nlm.nih.gov/pubmed/20635390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25557
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