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Identification of MiR-21-5p as a Functional Regulator of Mesothelin Expression Using MicroRNA Capture Affinity Coupled with Next Generation Sequencing

MicroRNAs (miRNAs) are small non-coding RNAs that regulate mRNA expression mainly by silencing target transcripts via binding to miRNA recognition elements (MREs) in the 3’untranslated region (3’UTR). The identification of bona fide targets is challenging for researchers working on the functional as...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: De Santi, Chiara, Vencken, Sebastian, Blake, Jonathon, Haase, Bettina, Benes, Vladimir, Gemignani, Federica, Landi, Stefano, Greene, Catherine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268774/
https://ncbi.nlm.nih.gov/pubmed/28125734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170999
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