Variation rs2235503 C > A Within the Promoter of MSLN Affects Transcriptional Rate of Mesothelin and Plasmatic Levels of the Soluble Mesothelin-Related Peptide

Soluble mesothelin-related peptide (SMRP) is a promising biomarker for malignant pleural mesothelioma (MPM), but several confounding factors can reduce SMRP-based test’s accuracy. The identification of these confounders could improve the diagnostic performance of SMRP. In this study, we evaluated th...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Silvestri, Roberto, Pucci, Perla, De Santi, Chiara, Dell’Anno, Irene, Miglietta, Simona, Corrado, Alda, Nicolí, Vanessa, Marolda, Daniela, Cipollini, Monica, Pellegrino, Enrica, Evangelista, Monica, Bonotti, Alessandra, Foddis, Rudy, Cristaudo, Alfonso, Landi, Stefano, Gemignani, Federica
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461867/
https://ncbi.nlm.nih.gov/pubmed/33014022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00975
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