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The Protein Structure Context of PolyQ Regions

Proteins containing glutamine repeats (polyQ) are known to be structurally unstable. Abnormal expansion of polyQ in some proteins exceeding a certain threshold leads to neurodegenerative disease, a symptom of which are protein aggregates. This has led to extensive research of the structure of polyQ...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Totzeck, Franziska, Andrade-Navarro, Miguel A., Mier, Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268486/
https://ncbi.nlm.nih.gov/pubmed/28125688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170801
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